Detailed clinical and specimen data associated with each phase of specimen accrual are meticulously recorded at each LCBRN Resource Site and entered into a secure, central database. All samples provided to investigators are annotated with the information listed below. De-identified pathology reports are also available for an additional fee.
Patient History
- Demographics – age, race, gender
- Height and weight
- History of prior malignancies
- Family history of lung cancer
- Military service, branch, year service began/ended
- History of carcinogen exposure (i.e. chemical, asbestos)
- Category of carcinogen exposure (military or civilian)
- Smoking history (pack-years)
- Prior treatment for any known lung cancer
Pre-op Surgery Data
- ECOG performance status
- Anatomic location of the tumor
- Two-dimensional tumor dimensions as measured on CT scan
- PET-CT maximal standard uptake value (SUV max)
- Presence or not of pleural effusion
- Presence or not of chest wall or mediastinal invasion
- Presence or not of a ground glass appearance of the tumor
Biofluid Procurement Data/Events
- Anesthetic status of patient at collection
- Time fluid collected from patient
- Time fluid received in processing lab
- Time fluid frozen
Surgery Data/Events
- Surgical approach
- Surgical procedure used to remove the procured tumor
- Overall surgical procedure
- Type of mediastinal lymph node dissection
- Clamp/ischemia time
- Time specimen excised from patient
Tissue Procurement Data/Events
- Time specimen received in surgical pathology
- Time specimen received by procurement technician
- Frozen specimen weight (g)
- Time specimen frozen/fixed
- Length of time in fixative
Post-Surgery Data
- Final clinical/pathologic stage
- Tumor histology
- Tumor grade
- Presence or not of lymphangio invasion
- Pre-operative treatment effect
- Presence or not of residual tumor
Follow-up Data
- Adjuvant therapies
- Evidence of recurrence at follow-up intervals
- Subsequent treatment post recurrence
- Post-procedure mortality and reason for death